Antituberculous Compoulous Compounds. I
نویسندگان
چکیده
منابع مشابه
Antituberculous therapy-induced toxicity.
Antituberculous drugs are generally safe but can occasionally be associated with life-threatening complications. This is a case report of neurotoxicity, acute respiratory distress syndrome (ARDS) and drug fever, occurring in a patient after initiation of antituberculous therapy (ATT).
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BACKGROUND Pyrazinamide is a paradoxical frontline tuberculosis drug characterized by high in vivo sterilizing activity but poor in vitro activity. This separation in pyrazinamide activity reflects differences between the in vivo tissue environment and in vitro culture conditions. The well-known acid pH requirement for pyrazinamide activity was discovered previously based on such reasoning but ...
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In this issue of the BJD, Ye et al.1 present data on T-cell-specific responses in patients with antituberculosis drug (ATD)-induced maculopapular exanthema (MPE) and drug reaction with eosinophilia and systemic symptoms (DRESS). Understanding these responses helps further our knowledge of the immunopathogenesis of antituberculous hypersensitivity, and ideally it would be translated into diagnos...
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Paradoxical reactions in tuberculosis have been reported in patients with tuberculous meningitis and appear as intracranial tuberculomas within 14-270 days of starting antituberculous therapy (ATT). Paradoxical reactions are due to the immune response of the host to ATT. They are commonly seen in the intensive phase of chemotherapy. However, paradoxical reactions occurring after completion of A...
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In a n c,," method fo r prepar ing aldoses labeled wit h Lritium at ca r bon l , Lhc aldoni c lactone l S rcdu ced with li thium boro.hyddde-I in p yridine soluLion . The mcthod is suitablc for prcparing aldosesl -1 h a vin g high specifi c act ivit ies. Thc crudc product con tains a substant ia l proport ion of t hc c<?lTespondin g a ldi tol-l-I, but t he purc aldosc-l-1 is rcadil y scparated ...
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ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1952
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.73.587